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Dr. Ching-Chi Chiu

-Associate Professor

in the Department of Medical Biotechnology and Laboratory Sciences

-Visiting Scholar

in the Picower institute for learning and memory of Massachusetts Institute of Technology (MIT).

https://tsailaboratory.mit.edu/members/

I'm the Associate Professor in the Department of Medical Biotechnology and Laboratory Science of Chang Gung University and Associate Research Fellow at Neuroscience Research Center of Chang Gung Memorial Hospital. My laboratory explores four interrelated research studies: (1) application of precision medicine in Alzheimer's disease (AD) and Parkinson's disease (PD), (2) molecular diagnosis of AD and PD, (3) development of induced pluripotent stem cell (iPSC) and CRISPR/Cas9 gene editing for cell therapy, (4) Identification of neuroprotective compounds using mutant gene knockin/knockout mice and transgenic mice model of AD and PD.

化工廠

Coauthor paper:

1. ABCA7 variants impact phosphatidylcholine and mitochondria in neurons. Nature. 2025 Nov;647(8089):462-471.

2.Resveratrol isomers with opposing activities target endonuclease G to modulate neurodegeneration and mitochondrial elimination. PNAS. 2026 Accepted.

CORE TECHNOLOGIES

Gene knockin and Knockout mice of PD
iPSCs of neurodegenerative diseases
Molecular diagnosis of neurodegenerative disorders
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Chang Gung University

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